Administration of Opioids

The major pharmacological treatment for acute pain persists to be opioids. Traditional methods of opioid direction are oral, intramuscular, subcutaneous and intravenous. Acute pain management has ameliorated with the introduction of developed techniques for administration of opioids (patient controlled analgesia [PCA] and epidural analgesia). Oral opioids are available as immediate-release (IR) and slow-release (SR) and can be used as step-down analgesia from epidurals or PCAs. Oral morphine has a bioavailability of about 30%--10 mg of IV morphine is roughly equivalent to 30mg of oral morphine.

  • Traditional Methods
  • Opioid-sparing Method
  • Chronic use of opioids

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